ELIXA also stands out from the other CVOT as it was the only trial enrolling patients with a recent acute coronary syndrome as opposed to CV events occurring 3 months before enrollment in all other trials
In the liver, it increases insulin sensitivity and reduces fat accumulation
Non-hormonal IUDs: ParaGard ParaGard is a non-hormonal form of birth control
STEP-HFpEF Trial Committees and Investigators, Kosiborod MN, Abildstrm SZ, Borlaug BA, Butler J, Rasmussen S, Davies M et al (2023) Semaglutide in patients with heart failure with preserved ejection fraction and obesity
cGAS-STING signaling in astrocytes and CNS inflammation In astrocytes, AD model mice (5xFAD) crossed with the Cgas / line exhibited a reduction in GFAP + cell area, indicating the involvement of the cGAS-STING pathway (Xie et al., 2023)